| Description |
1 online resource |
| ISBN |
9781118444153 (ePub) |
|
1118444159 (ePub) |
|
9781118444092 (Adobe PDF) |
|
1118444094 (Adobe PDF) |
|
9781118444122 |
|
1118444124 |
|
9781118444160 |
|
1118444167 |
|
9781118444160 (cloth) |
| Publ No |
EB00257519 Recorded Books |
| Bibliography |
Includes bibliographical references and index. |
| Access |
Access restricted to subscribing institutions. |
| Summary |
"Widely recognized as one of the most important signaling mechanisms in development and disease, Wnt signaling pathways are networks of proteins that play significant roles in embryogenesis or cancer development. Wnt Signaling in Development and Disease addresses the fundamentals of Wnt signaling and delves into molecular pathway mechanisms, its role in embryogenesis, adult tissue homeostasis, and chronic disease. This comprehensive resource details current knowledge of Wnt signaling while looking ahead to future progress"--Provided by publisher. |
| Note |
Print version record and CIP data provided by publisher. |
| Contents |
Wnt Signaling in Development and Disease; Copyright; Contents; Contributors; Preface; Part 1 Molecular Signaling Mechanisms: From Pathways to Networks; 1 Wnt Signal Production, Secretion, and Diffusion; Introduction; Posttranslational modification of Wnt; The Wnt secretion pathway; Mechanisms that promote and control the diffusion of Wnt; Conclusions and perspectives; References; 2 Wnt Signaling at the Membrane; Introduction; The Frizzled family of Wnt receptors; The LRP family of Wnt coreceptors; References |
|
Wnt/rho/ ROCK and Wnt/rac/ JNK signalingWnt/Ror signaling; Wnt/Ryk signaling; Wnt/ cAMP /protein kinase A; Wnt/ TOR signaling; Outlook; References; 7 Molecular Mechanisms of Wnt Pathway Specificity; Early Wnt classifications; Wnt5a exemplifies the ability of Wnts to activate multiple signaling cascades; Multiple signaling routes through single Frizzled family members; Determinants of Wnt pathway specificity; Perspectives; Acknowledgments; References; 8 Modulation of Wnt Signaling by Endocytosis of Receptor Complexes; Introduction; Endocytic pathways |
| Link |
Print version: Wnt signaling in development and disease. Hoboken, New Jersey : John Wiley & Sons, [2014] 9781118444160 (DLC) 2013042745 |
| Subject |
Wnt proteins.
|
|
Cellular signal transduction.
|
| Other Author |
Hoppler, Stefan, 1965- editor.
|
|
Moon, Randall T., editor.
|
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